Table 2 Predicted biological functions suppressed by curcumin in epididymal white adipose tissue of Western diet-induced obese mice (also refer Table S4).
Predicted biological function decreased by curcumin | P | Activation z-score |
|---|---|---|
Quantity, activation, homing, uptake of cells | 3.85E–03–4.85E–02 | −3.274 to −2.133 |
Quantity, cell movement, homeostasis, activation, differentiation, homing, immune response, phagocytosis of leukocytes | 2.59E–03–4.73E–02 | −3.396 to −2.012 |
Homing of lymphocytes | 4.63E–02 | −2.671 |
Cell movement, activation, response, migration, engulfment of myeloid cells | 8.11E–04–4.39E–02 | −3.627 to −2.018 |
Engulfment, phagocytosis of blood cells | 1.08E–02 | −2.524 to −2.445 |
Phagocytosis of red blood cells | 2.12E–02 | −2 |
Cell movement, migration, response, degranulation, accumulation, Cell viability, engulfment, cell rolling, cytotoxicity of phagocytes | 9.36E–04–4.20E–02 | −3.695 to −2.028 |
Cell movement of antigen-presenting cells | 1.03E–02 | −2.244 |
Cell movement, chemotaxis, orientation of macrophages | 3.90E–03–2.66E–02 | −2.7 to −2.198 |
Cell movement, cell rolling of granulocytes | 6.52E–03–3.39E–02 | −3.856 to −2.54 |
Cell movement, homing, chemotaxis, recruitment, cell rolling of neutrophils | 1.81E–03–4.97E–02 | −4.286 to −2.044 |
Quantity of peripheral T lymphocyte | 2.34E–03 | −2.236 |
Cell movement of natural killer cells | 2.78E–02 | −2.036 |
Recruitment of mast precursor cells | 2.12E–02 | −2 |
Degranulation, adhesion of mast cells | 7.45E–03–1.01E–02 | −2.425 to −2.079 |
Inflammatory response | 1.11E–02 | −2.483 |
Synthesis, production of reactive oxygen species | 3.06E–05–1.29E–04 | −3.136 to −2.62 |
Production of superoxide | 4.19E–03 | −2.319 |
Synthesis of protein | 2.51E–02 | −2.236 |
