Table 2 Ten lncRNAs with higher core degrees in the co-expression network.
LncRNA | Seqname | Core Degree | Fold Change | Regu-lation | GO analysis | Pathway analysis |
|---|---|---|---|---|---|---|
RP11-340F14.5 | ENST00000569999 | 28 | 3.50 | up | immune response (GO: 0006955), inflammatory response (GO: 0006954), leukocyte migration (GO: 0050900), positive regulation of phosphatidylinositol 3-kinase signaling (GO: 0014068) | Osteoclast differentiation (hsa04380), Chemokine signaling pathway (hsa04062), NOD-like receptor signaling pathway (hsa04621) |
RP11-382B18.4 | ENST00000602453 | 27 | 6.56 | up | immune response (GO: 0006955), inflammatory response (GO: 0006954), negative regulation of MAP kinase activity (GO: 0043407), cell differentiation (GO: 0030154) | Phagosome (hsa04145), NOD-like receptor signaling pathway (hsa04621) |
NAPSB | NR_002798 | 25 | 3.02 | up | immune response (GO: 0006955), inflammatory response (GO: 0006954), positive regulation of protein kinase B signaling (GO: 0051897), negative regulation of MAP kinase activity (GO: 0043407), | Phagosome (hsa04145), NOD-like receptor signaling pathway (hsa04621) |
CTB-83J4.2 | ENST00000596330 | 24 | 3.40 | up | immune response (GO: 0006955), inflammatory response (GO: 0006954), extracellular matrix disassembly (GO: 0022617), positive regulation of phosphatidylinositol 3-kinase signaling (GO: 0014068) | Phagosome (hsa04145), NOD-like receptor signaling pathway (hsa04621) |
XLOC_008644 | TCONS_00018359 | 24 | 3.70 | up | immune response (GO: 0006955), neutrophil chemotaxis (GO: 0030593), inflammatory response (GO: 0006954), negative regulation of MAP kinase activity (GO: 0043407), | Phagosome (hsa04145), NOD-like receptor signaling pathway (hsa04621) |
RP11-559N14.5 | ENST00000588565 | 22 | 3.22 | down | fatty acid biosynthetic process (GO: 0006633), biotin metabolic process (GO: 0006768), fatty acid beta-oxidation using acyl-CoA dehydrogenase (GO: 0033539), regulation of glucose metabolic process (GO: 0010906) | AMPK signaling pathway (hsa04152), Adipocytokine signaling pathway (hsa04920), Insulin resistance (hsa04931) |
IQCF4 | NR_038214 | 22 | 2.96 | down | negative regulation of actin filament polymerization (GO: 0030837), cell migration involved in sprouting angiogenesis (GO: 0002042), cellular response to calcium ion (GO: 0071277) | Null |
RP11-363E7.4 | ENST00000563205 | 20 | 2.05 | down | low-density lipoprotein particle remodeling (GO: 0034374), fatty acid biosynthetic process (GO: 0006633), oxaloacetate metabolic process (GO: 0006107), regulation of glucose metabolic process (GO: 0010906) | AMPK signaling pathway (hsa04152), Metabolic pathways (hsa01100), Renin-angiotensin system (hsa04614) |
XLOC_012574 | TCONS_00026160 | 20 | 5.09 | up | immune response (GO: 0006955), neutrophil chemotaxis (GO: 0030593), inflammatory response (GO: 0006954), negative regulation of MAP kinase activity (GO: 0043407), | Osteoclast differentiation (hsa04380), Lysosome (hsa04142) |
RP11-707P17.1 | ENST00000561007 | 18 | 3.30 | down | biotin metabolic process (GO: 0006768), fatty acid biosynthetic process (GO: 0006633), regulation of glucose metabolic process (GO: 0010906), positive regulation of cellular metabolic process (GO: 0031325) | Metabolic pathways (hsa01100), Insulin signaling pathway (hsa04910), Glycolysis/Gluconeogenesis (hsa00010) |
