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Figure 1

From: Milk cholesterol concentration in mice is not affected by high cholesterol diet- or genetically-induced hypercholesterolaemia

Figure 1

Plasma lipids. (a) Total plasma cholesterol levels were measured in whole plasma using a commercially available enzymatic assay (WT Chow, n = 5; WT HC, n = 5; Abcg8 −/− Chow, n = 4; Abcg8 −/− HC, n = 5; Ldlr −/− Chow, n = 8; Ldlr −/− HC, n = 5). Data are presented as median and interquartile range (Tukey). Statistical significance was tested with Kruskal-Wallis post-hoc Conover-Inman; non-different groups share a letter. The threshold of significance was p < 0.05. (b–d) Cholesterol in lipoprotein fractions following separation by FPLC of pooled plasma samples and (e) VLDL + LDL to HDL cholesterol ratios calculated from these results (WT Chow, n = 5; WT HC, n = 5; Abcg8 −/− Chow, n = 4; Abcg8 −/− HC, n = 5; Ldlr −/− Chow, n = 4; Ldlr −/− HC, n = 4). □: low cholesterol diet (Chow); ■: high cholesterol diet (HC).

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