Figure 2

Hepatic cholesterol levels. Hepatic lipids were extracted according to Bligh & Dyer and measured by gas chromatography (WT Chow, n = 5; WT HC, n = 5; Abcg8 −/− Chow, n = 4; Abcg8 −/− HC, n = 5; Ldlr −/− Chow, n = 8; Ldlr −/− HC, n = 5). Data are presented as median and interquartile range (Tukey). □: low cholesterol diet (Chow); ■: high cholesterol diet (HC). Statistical significance was tested with Kruskal-Wallis post-hoc Conover-Inman; non-different groups share a letter. The threshold of significance was p < 0.05.