Figure 3

(a) Cartoon representation of S. pombe Dnmt2 crystal structure (yellow) co-crystallized with S-adenosyl-homocysteine depicted as sticks (grey). The crystal structure was refined at 1.7 Å. (b) Superposition of Dnmt2 crystal structures from S. pombe (yellow), H. sapiens (pink) and E. histolytica (blue) shown as cartoons.