Figure 6 | Scientific Reports

Figure 6

From: Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine

Figure 6

(a) Predicted model of the Dnmt2-tRNA complex. spDnmt2 and yeast tRNAAsp (1VTQ) were docked computationally using Rosetta. spDnmt2 surface is depicted with surface electrostatics (±5.0 kBT/e). tRNAAsp is shown as cartoon with orange ribose-phosphate backbone and yellow bases. (b) Zoomed view into the active site. Queuine 34, cytosine 38 and S-adenosyl-homocysteine (SAH) are presented as balls and sticks.

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