Figure 6
(i) Impact of varying concentrations of phytofabricated AgNPs on L. donovani viability. (ii) Cytotoxicity assessment of AgNPs shows the relation between parasite (red curve) and monocyte (blue curve) viability as a function of AgNP concentration (p- value for * was < 0.0001, n = 3). (iii) Comparative analysis of the % viability of monocyte at IC50 values of AgNP and Miltefosine (p- value for * was < 0.0001, n = 4). Microscopic images of monocyte cell line observed at 40X magnification (iv) negative control (untreated cells), (v) test sample (cells treated with AgNPs at IC50 concentration), and (vi) positive control (cells treated with miltefosine at IC50 concentration). The blue circle shows healthy monocytes and red circle shows deformed, ruptured, and dead cells.
