Figure 6
From: Chemokine CXCL16 mediates acinar cell necrosis in cerulein induced acute pancreatitis in mice
Expression of Ccl9 by pancreatic acinar cells. (A) Amylase secretion by the rat acinar cell line AR42J upon stimulation with various concentrations of cerulein. (B) Cxcl16 and Ccl9 mRNA expression by AR42J upon stimulation with cerulein. (C) Ccl9 mRNA expression of AR42J upon stimulation with cerulein (10−10 M) in combination with various concentrations of recombinant Cxcl16 protein (left). Ccl9 mRNA expression of AR42J upon stimulation with cerulein (10−7 M) in the presence of neutralizing anti-Cxcl16 Ab or control Ab (right). (D) Cxcl16 and Ccl9 mRNA expression by pancreatic acinar cells isolated from WT and Cxcl16−/− mice upon stimulation with cerulein (10−7 M). *p < 0.05 Results were shown as mean ± SD.
