Figure 7
From: Chemokine CXCL16 mediates acinar cell necrosis in cerulein induced acute pancreatitis in mice
Therapeutic effects of neutralizing Cxcl16 Ab in the necrotizing pancreatitis model. (A) Injection protocol of anti-Cxcl16 Ab in necrotizing pancreatitis model. (B) Serum amylase level, (C) representative H&E sections, and pathology score of control Ab or anti-Cxcl16 Ab-treated mice at 39 h. (D) Gr1 immunostained sections and neutrophil counts of control Ab or anti-Cxcl16 Ab-treated mice at 39 h. (E) Pancreatic Ccl9 mRNA, pancreatic Ccl9 protein, and serum Ccl9 protein levels in control Ab or anti-Cxcl16 Ab-treated mice at 39 h. n = 5 in each group. *p < 0.05 Results were shown as mean ± SD.
