Figure 3 | Scientific Reports

Figure 3

From: Expression of human mutant cyclin dependent kinase 4, Cyclin D and telomerase extends the life span but does not immortalize fibroblasts derived from loggerhead sea turtle (Caretta caretta)

Figure 3

Establishment of Cyclin-dependent kinase 4 (CDK4)-, Cyclin D- and telomerase-expressing cells derived from the loggerhead sea turtle. (A) left panel, cell morphology of the loggerhead-derived cells, expressing CDK4, Cyclin D, and telomerase. Right panel, cell morphology of the loggerhead primary cells. (B) Protein expression of the introduced CDK4 and Cyclin D. The expression of human CDK4, human Cyclin D, and endogenous tubulin were detected by using western blot analysis. Lane 1, primary A634 cell line; Lane 2, A634-K4DT cell line; Lane 3, primary A640 cell line; Lane 4, A640-K4DT cell line.

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