Figure 4
From: Brain Cell Type Specific Gene Expression and Co-expression Network Architectures
Correlation of genewise cell type enrichment measures with PubMed text mining results within cell types. For each of the six cell types, i.e. the astrocyte (a), endothelial cell (b), microglia (c), neuron (d), oligodendrocyte (e), and oligodendrocyte precursor cell (f), the top 100 gene symbols most enriched in that cell type are plotted against the number of PubMed abstracts that mention both that gene symbol as well as the corresponding cell type. The Spearman correlation between these measures was calculated. Several gene symbols were chosen for highlighting, including gene symbols that have not been mentioned in a PubMed abstract with that cell type to date (labeled red). Note that for oligodendrocyte precursor cells (OPCs), the cell type name used in the PubMed search was “oligodendrocyte precursor.”
