Table 2 Concordance between Genotype MTBDRsl and Bactec MGIT-960 based second-line drug susceptibility testing.

From: Association of gyrA and rrs gene mutations detected by MTBDRsl V1 on Mycobacterium tuberculosis strains of diverse genetic background from India

Genotype MTBDR sl

SLD by Bactec MGIT 960

Sensitive (%)

FQ mono-resistant (%)

AG/CP mono-resistant (%)

XDR (%)

Concordance (%)

k coeff

Sensitive (232) (64.6%)

225 (97)

7(3.0)

—

—

97

0.92 Perfect

FQ- resistant (108) (30%)

6(5.5)

101 (93.5)

—

1(0.9)

93.5

0.89 Perfect

AG/CP- resistant (2) (0.5%)

—

1(50)

1 (50)

—

50

0.66 Substantial

XDR (17) (4.7%)

—

1(5.9)

—

16(94.1)

94.1

0.93 Perfect

Total (359)

231 (64.4)

110 (30.6)

1 (0.3)

17 (4.7)

—

 
  1. FQ- Fluoroquinolone, AG- Aminoglycosides, CP-Cyclopeptide.
  2. k coeff.- Cohens’s kappa as a measure of agreement between two values.
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