Table 2 Median (range) number of inflammatory cells and fungal load per mm2 in the skin lesion sample biopsied at T1 of the 52 cats with sporotrichosis according to outcome of itraconazole treatment and positive serology for FIV or FeLV.

From: Clinical features, fungal load, coinfections, histological skin changes, and itraconazole treatment response of cats with sporotrichosis caused by Sporothrix brasiliensis

Cells/yeasts

Median (range) number of cells/mm2 in the biopsied skin lesion

Total (n = 52)

Outcome (n = 52)

pa

FIV/FeLV (n = 48)

pa

TF (n = 15)

CC (n = 37)

Positive (n = 12)

Negative (n = 36)

Neutrophils

171.1 (29.6–381.0)

139.5 (53.2–234.4)

152.7 (47.6–239.2)

0.785

119.4 (47.6–173.4)

144.2 (87.4–239.2)

0.021*

Macrophages

131.0 (9.0–1576.0)

121.6 (80.6–157.2)

122.2 (65.4–175.2)

0.317

105.6 (80.6–170.6)

127.4 (65.4–175.2)

0.938

Lymphocytes

29.6 (13–106.4)

29.8 (14.0–106.4)

29.6 (18.4–41.8)

0.793

30.6 (18.0–40.0)

25.8 (14.0–106.4)

0.482

Plasma cells

13.8 (0–89.2)

11.6 (0.6–46.8)

15.6 (0–89.2)

0.739

15.6 (3.8–33.0)

11.0 (0–89.2)

0.543

Mast cells

9.4 (0–28.2)

7.7 (0.6–12.6)

9.7 (0.8–20.8)

0.443

8.5 (3.2–20.8)

9.2 (0.6–15.2)

0.858

MGC

0 (0–3.4)

0 (0–0.2)

0 (0–3.4)

0.844

0 (0–0.2)

0 (0–3.4)

0.858

Eosinophils

0 (0–5.6)

0 (0–1.8)

0 (0–1.6)

0.87

0 (0–1.2)

0 (0–1.8)

0.674

Yeasts

38.1 (0–1,274.8)

745.5 (2.2–1,274.8)

204.9 (0.8–928.0)

0.002*

717.1 (10.0–1,274.8)

309.2 (0.8–864.0)

0.095

  1. MGC, multinucleated giant cells; n, number of cats; TF, treatment failure; CC, clinical cure; aMann-Whitney test. *Significant difference (p < 0.05).
Back to article page