Figure 2

CMC of C2 electrode from typical subjects. CMC values before intervention (Pre), at the fourth week (4 wk), after completing 8 weeks of intervention (8 wk), and 4 weeks follow-up (f/u) for one subject in the ES group (dark line) and one subject in the control group (dashed line) were shown. The C2 electrode was chosen here because both subjects had right hemisphere stroke and C2 is the closet the right primary motor cortex hand area. The red line represents the critical threshold (0.0859) calculated by the equations described in Methods section. At the fourth week, the subject in the ES group had more area in beta band above the critical threshold, indicating the motor cortex had greater and physiologically meaningful functional connectivity with corresponding muscles.