Figure 3 | Scientific Reports

Figure 3

From: Diagnosis of Human Leptospirosis in a Clinical Setting: Real-Time PCR High Resolution Melting Analysis for Detection of Leptospira at the Onset of Disease

Figure 3

Sensitivity of molecular assays in function of the kinetics of disease progression. Comparative analysis of positive samples by nested PCR and qRT-PCR-HRM through the three early leptospirosis stages: onset (serum positive), dissemination and kidney colonization (serum and urine positive) and excretion (urine positive). (a) Comparison with primer pair LFB1. (b) Comparison with primer pair G1/G2. Statistics by Fisher Exact test, A p = 0.0033 and B p = 0.0763.

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