Figure 7
From: Plasmonic Optical Imaging of Gold Nanorods Localization in Small Animals
The GNR, imaging system and reconstruction workflow for SPROT imaging. (a) GNR had 10 nm diameter and 45 nm length, leading to peak absorption at 850 nm (b). (c) The integrated XCT/DOT system. The XCT system consists of an x-ray source, a rotation stage and a flat panel detector. The DOT system consists of a laser source whose trajectory projects through the XCT image isocenter, a 45° mirror and a lens-coupled CCD camera. A lead block stands between the camera and XCT assembly to shield the scattered x-ray. (d) SPROT reconstruction workflow. XCT scan was used to acquire the object volume for 3D mesh generation. Optical images were processed to extract surface fluence data which was then mapped to the 3D mesh. The 3D mesh, surface fluence data and locations of laser source were input for SPROT reconstruction.
