Table 2 Hemodynamics of PPVL rats.

From: The soluble guanylate cyclase stimulator riociguat reduces fibrogenesis and portal pressure in cirrhotic rats

 

SO-VEH

p SO-VEH vs. PPVL-VEH

PPVL-VEH

PPVL-RIO

p PPVL-VEH vs. PPVL-RIO

n

5

 

7

7

 

Weight (g)

351 ± 13

0.305

338 ± 20

335 ± 14

0.714

MAP (mmHg)

92 ± 8.1

0.634

87 ± 6.3

75 ± 9.5

0.045

Heart rate (bpm)

353 ± 23

0.128

327 ± 26

314 ± 37

0.734

SMABF (mL/min/100 g)

4.1 ± 1.8

<0.001

11.7 ± 2.2

14.0 ± 1.6

0.446

Portal pressure (mmHg)

6.5 ± 1.0

0.005

12.7 ± 1.6

10.7 ± 0.9

0.025

Shunting (%)

8.5 ± 3.9

0.011

45.9 ± 20.1

77.5 ± 13.7

0.007

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