Table 1 A summary of the simulation results
From: Testing for Sufficient-Cause Interactions in Case-Control Studies of Non-Rare Diseases
Proposed method | Risk-scale RERI test | Odds-scale RERI test | Odds-scale PRISM test | |
|---|---|---|---|---|
Type I error rate | Stable at 0.05 for all scenarios. | Extremely small, very conservative test. | Small at low disease prevalence values, but inflated when the disease prevalence is greater than 0.4. | Stable at 0.05 at low disease prevalence, but inflated even at low disease prevalence values with larger sample sizes. |
Power | Reached more than 80% in all scenarios. | Much less powered compared with the proposed method | Much less powered compared with the proposed method | Comparable to (when the disease prevalence is 0.02) and greater than (when the disease prevalence is greater than 0.2) those of the proposed method. |
