Figure 5

IL-8 expression as a function of ERK1/2 and p38 activation. In addition to analyzing MAPK activation based on and high and low responder status, we analyzed the data in continuous format in which the ratio of activated protein (X-axis) was plotted against ozone mediated IL-8 induction. This comparison was made for both ERK1/2 (A) as well as p38 (B). Figures were created using the same donors as depicted in Fig. 4 (n = 12; 6 high and 6 low responders).