Table 2 Variables after screened by the analysis of covariance.

From: Warfarin maintenance dose Prediction for Patients undergoing heart valve replacement— a hybrid model with genetic algorithm and Back-Propagation neural network

Included variables (unit)

partial η2

Age (year)

0.002

EF (%)

0.001

Left ventricular diastolic diameter (mm)

0.001

Operation history

0.001

Albumin (g/L)

0.001

Urea nitrogen (mmol/L)

0.001

Creatinine (umol/L)

0.003

preoperative APTT of one day before valve replacement (s)

0.004

Warfarin origin

0.66

The time of first anticoagulant (d)

0.06

  1. Note: APTT: Activated partial thromboplastin time.
  2. EF: Ejection fraction.
  3. Operation history: it is a categorical variable and means whether the included patient has done other surgery before heart valve replacement, we used 1 to represent patient not having done other surgery and 2 to represent patient having done other surgery.
  4. Warfarin origin: it is also a categorical variable and means where the warfarin is made in, China or abroad, we used 1 to represent warfarin made in China and 2 to represent warfarin made abroad.
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