Table 1 Demographic and clinical characteristics of hyperuricemic patients and normouricemic controls.

From: Genetic association and functional analysis of rs7903456 in FAM35A gene and hyperuricemia: a population based study

Characteristics

Male

P value

Female

P value

Patients

Controls

Patients

Controls

Number

770

1,408

NA

211

384

NA

Age (years), mean ± SD

44.73 ± 8.55

44.81 ± 8.45

0.8327

46.24 ± 8.63

46.13 ± 8.04

0.8802

BMI (kg/m2)

25.5 ± 1.27

23.6 ± 0.88

<0.001

23.7 ± 0.75

22.8 ± 0.58

<0.001

Total cholesterol (mmol/L)

4.18 ± 0.57

3.91 ± 0.53

<0.001

4.22 ± 0.54

3.93 ± 0.57

<0.001

Triglycerides (mmol/L)

2.36 ± 0.42

1.79 ± 0.30

<0.001

1.84 ± 0.28

1.57 ± 0.33

<0.001

LDL-C (mmol/L)

2.44 ± 0.28

2.21 ± 0.29

<0.001

2.47 ± 0.30

2.26 ± 0.33

<0.001

HDL-C (mmol/L)

1.11 ± 0.18

1.15 ± 0.19

<0.001

1.17 ± 0.17

1.19 ± 0.20

0.2041

Fasting glucose (mmol/L)

5.21 ± 0.47

4.78 ± 0.44

<0.001

5.18 ± 0.42

4.66 ± 0.41

<0.001

Creatinine (μmol/L)

91.42 ± 7.95

77.68 ± 8.24

<0.001

72.75 ± 7.60

67.21 ± 7.33

<0.001

Urea nitrogen (mmol/L)

5.21 ± 0.69

4.73 ± 0.68

<0.001

4.69 ± 0.63

4.18 ± 0.60

<0.001

Uric acid (μmol/L)

462.84 ± 44.20

404.52 ± 27.15

<0.001

298.52 ± 52.22

234.52 ± 35.85

<0.001

  1. SD: standard deviation; BMI, body mass index; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; NA, not applicable.