Table 1 The general characteristics of the subjects.
Characteristics | The discovery stage | P-value | The replication stage | P-value | ||
|---|---|---|---|---|---|---|
Cases (N = 1,052) | Controls (N = 2,117) | Cases (N = 1,173) | Controls (N = 2,362) | |||
Age (years, mean ± SD) | 60.79 ± 7.32 | 61.12 ± 7.62 | 0.234 | 61.43 ± 8.04 | 60.88 ± 7.99 | 0.056 |
Gender (Female/Male) | 601/451 | 1,217/900 | 0.848 | 640/533 | 1,297/1,065 | 0.831 |
BMI (kg/m2, mean ± SD) | 26.26 ± 1.52 | 25.74 ± 1.51 | <0.001 | 26.42 ± 1.58 | 25.87 ± 1.55 | <0.001 |
K-L grading (%) | ||||||
Grade 2 | 506 (48.10%) | NA | NA | 536 (45.69%) | NA | NA |
Grade 3 | 319 (30.32%) | NA | NA | 377 (32.14%) | NA | NA |
Grade 4 | 227 (21.58%) | NA | NA | 260 (22.17%) | NA | NA |
