Figure 5
From: Allostery and cooperativity in multimeric proteins: bond-to-bond propensities in ATCase

To investigate homotropic cooperativity, the six PALA substrates were selected as the source on the active unligated R state. The structure on the right shows just one half on the protein for clarity and here it is clear that the highest scoring regions (in red) of ATCase are located around the active and allosteric sites.