Figure 5
From: Complex spectrum of phenobarbital effects in a mouse model of neonatal hypoxia-induced seizures
Assessment of neuronal injury 72 h post KA challenge. (A,B) Representative 20x photomicrographs of Fluoro-Jade B staining following KA challenge. Hippocampal sections show positive FJB positive cells mainly in the CA1 region of all groups, hypoxia mice show the greatest number of FJB positive cells. Scale bar: 100 μm. (B,C) Graph shows number of FJB positive cells in the CA1 subfield of the hippocampus (B), CA3 (C, Top) and Hilus (C, Bottom) (n = 6–7 per group *p < 0.05 compared to control group). Note: Hypoxia exposed mice show an increase in FJB positive cells in the CA1 subfield of the hippocampus, no differences were observed in the CA3 and Hilus.
