Figure 5
Scheme of exposure of experimental mouse model. BALB/c mice (n = 32) were randomly distributed in 2 groups (16 per group) and were kept one week under acclimation conditions. Both the control and exposure group received a single intraperitoneal injection 12.5 mg/kg of AOM a week before the start of the experiment and DSS 2% dissolved in water ad libitum between day 1 and 5 respectively (light grey line). From day 1 to 21, E171 group received 5 mg/kg body weight by oral gavage of E171 dispersed in water 5 days per week (black line). The control group kept on receiving a vehicle (sterile water). *2 males and 2 females were sampled.
