Figure 1 | Scientific Reports

Figure 1

From: Downregulation of WNT11 is associated with bladder tissue fibrosis in patients with interstitial cystitis/bladder pain syndrome without Hunner lesion

Figure 1

Comparison of gene expression associated with IC/BPS pathology between NHIC and HIC patient bladder tissues. (a–f) RQ-PCR analysis of the known biomarkers of IC/BPS, including those of inflammation (a), growth factors (b), apoptosis (c), nitric oxide synthase (d), acetylcholine neurotransmitter biosynthesis (e), and transcription regulators (f) in the bladder tissues of the indicated patient groups. Gene expression is presented as a percentage of GAPDH. Data are represented as a dot plot of mean ± SEM [n = 6 for non-IC; n = 11 for non-Hunner-type IC (NHIC) and n = 19 for Hunner lesions in Hunner-type IC (HIC); *p < 0.05 using one-way ANOVA analysis with a Bonferroni post-hoc test]. Non-IC, stress urinary incontinence patients.

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