Figure 3 | Scientific Reports

Figure 3

From: Downregulation of WNT11 is associated with bladder tissue fibrosis in patients with interstitial cystitis/bladder pain syndrome without Hunner lesion

Figure 3

Morphological changes following silencing of WNT family genes in HBlEpC. (a) RQ-PCR analysis of the indicated genes in HBlEpC primary bladder epithelial cells at 4 days after infection with lentivirus containing each shRNA construct. Data normalised to the scramble control group (shCTR) are represented as mean ± SEM, n = 4, ***p < 0.001 using one-way ANOVA analysis. (b–f) Representative image of HBlEpC at the indicated days after infection with lentivirus containing shWNT11 (b), shWNT2B (c), shWNT5A (d), shWNT10A (e), and shHB-EGF (f) or scramble control (shCTR) construct (magnification x100, scale bar = 100 μm).

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