Figure 7 | Scientific Reports

Figure 7

From: Downregulation of WNT11 is associated with bladder tissue fibrosis in patients with interstitial cystitis/bladder pain syndrome without Hunner lesion

Figure 7

Increased fibronectin extracellular matrix protein by knockdown of WNT family genes. (a–d) Immunofluorescent staining of fibronectin (green), an extracellular matrix protein in HBlEpC cells, at 7 days after infection with lentivirus containing shWNT11 (a), shWNT2B (b), shWNT5A (c), and shWNT10A (d) constructs (magnification x200, scale bar = 100 μm). The higher magnification images (magnification x400, scale bar = 50 μm) are inserted in the lower left corner in each image. Nuclei were stained with DAPI (blue). A scramble shRNA construct was used as the control.

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