Figure 1

Composition of the vaginal microbiota during menses as determined by culturomic analysis as a function of vaginal colonization by S. aureus. (A) Between-class analysis was performed at the bacterial genus level. Thirty-six samples were from women vaginally colonized by S. aureus (green) and 46 samples from women not colonized by S. aureus (yellow). The analysis was supported by a Monte Carlo test (p = 0.026). The data include the distribution of bacterial genera according to their contribution to differentiation of the vaginal microbiota of women carrying or not carrying S. aureus. (B) Heatmap showing the average relative proportion of the 10 microbial genera most commonly associated with vaginal carriage of S. aureus (left) and 10 microbial genera most often associated with the absence of S. aureus at the vaginal stage (right) in samples containing (lower line) and not containing S. aureus (upper line). Heatmap unit is a percentage of the average relative proportion of taxa.