Figure 4
From: Light Emitting Diodes based Photoacoustic Imaging and Potential Clinical Applications

(a) PA and US combined image from a human MCP joint affected by inflammatory arthritis. (b) PA and US combined image from an MCP joint of a normal volunteer. PA images in (a) and (b) were scanned by the LED-based PA system (850-nm wavelength) using the same level of gain and the same number of signal averaging. (c) Quantified synovial microvascular density in the arthritic joints vs. the normal joints (n = 4 for each group). The asterisk on red line shows the mean value, and the distance above or below it shows the standard deviation. A p-value of 0.0143 for a two-tailed t-test demonstrates the capability of PA imaging in differentiating arthritic joints from normal joints based on the detecting of enhanced microvasculature as a result of inflammation.