Figure 4
From: Age at first birth in women is genetically associated with increased risk of schizophrenia
Genetic correlation (left) and heritability (right) of age at first birth (AFB) ≥ 26, AFB < 26, and schizophrenia (SCZ). Cor(AFB < 26, AFB ≥ 26): Estimated genetic correlation between the groups with AFB < 26 and with AFB ≥ 26. Cor(SCZ, AFB ≥ 26): Estimated genetic correlation between SCZ and AFB in the older AFB group. Cor(SCZ, AFB < 26): Estimated genetic correlation between SCZ and AFB in the younger AFB group. The bars are standard errors. In the model, the AFB phenotypes were adjusted for age at interview, year of birth, assessment center at which participant consented, genotype batch and the first 20 principal components. And the SCZ phenotypes were adjusted for sex, cohorts and the first 20 principal components. The sample size for group AFB ≥ 26 was 17,598 and for group AFB < 26 was 21,294, and for group SCZ was 41,630.
