Table 3 Logistic Regression Model of Hyperglycemia as a Risk Factor for a Poor 3-Month Outcome in Patients with Acute Ischemic Stroke of the Anterior Circulation after Endovascular Revascularization Therapy According to Reperfusion Status.

From: Impact of varying levels of hyperglycemia on clinicoradiographic outcomes after endovascular reperfusion treatment

 

Overall (n = 341)

Reperfusion subgroup (n = 272)

Non-reperfusion subgroup (n = 69)

OR (95% CI)

p-value

OR (95% CI)

p-value

OR (95% CI)

p-value

Age

1.05 (1.03–1.08)

<0.001

1.05 (1.02–1.08)

0.001

1.07 (1.01–1.14)

0.030

Sex

0.94 (0.55–1.62)

0.826

0.92 (0.49–1.71)

0.793

1.43 (0.36–5.73)

0.616

Premorbid mRS score

 

0.083

 

0.126

 

0.598

  mRS0

Reference

 

Reference

 

Reference

 

  mRS1

2.37 (1.05–5.35)

0.039

2.40 (0.94–6.14)

0.068

4.72 (0.50–44.61)

0.176

  mRS2

4.53 (1.13–18.18)

0.033

4.69 (1.08–20.44)

0.040

—

0.999

  mRS3

1.13 (0.23–5.58)

0.879

1.81 (0.29–11.21)

0.525

0.47 (0.01–21.22)

0.700

  mRS4

2.12 (0.06–78.41)

0.684

2.43 (0.07–89.64)

0.629

  

Admission NIHSS score

1.12 (1.06–1.19)

 < 0.001

1.12 (1.05–1.20)

0.001

1.19 (1.01–1.39)

0.035

IV tPA

1.134 (0.58–2.22)

0.714

1.14 (0.52–2.50)

0.735

1.49 (0.22–10.15)

0.682

Baseline intracranial occlusion

 

0.917

 

0.775

 

0.904

  ICA T

Reference

 

Reference

 

Reference

 

  ICA I

1.01 (0.33–3.09)

0.993

0.88 (0.27–2.95)

0.840

3.68 (0.03–503.34)

0.604

  MCA M1

1.00 (0.54–1.88)

0.990

0.92 (0.45–1.87)

0.822

0.84 (0.16–4.46)

0.835

  MCA M2 superior

0.54 (0.12–2.32)

0.403

0.29 (0.05–1.94)

0.203

1.20 (0.22–6.44)

0.999

  MCA M2 inferior

1.28 (0.36–4.62)

0.706

1.21 (0.27–5.44)

0.804

—

0.471

Pre-treatment DWI volume

1.02 (1.01–1.03)

0.002

1.02 (1.01–1.03)

0.002

1.00 (0.98–1.02)

0.704

Onset to puncture

1.00 (1.00–1.00)

0.044

1.00 (1.00–1.01)

0.025

1.00 (1.00–1.01)

0.604

Final mTICI 2b–3

0.24 (0.12–0.46)

<0.001

    

PH2 or SAH 3–4

8.25 (2.15–31.66)

0.002

3.97 (0.88–17.89)

0.073

—

0.999

Glucose level

 

0.014

 

0.171

 

0.007

  Normoglycemia

Reference

 

Reference

 

Reference

 

  Moderate hyperglycemia

2.37 (1.26–4.45)

0.007

1.86 (0.90–3.82)

0.094

10.99 (2.15–56.25)

0.016

  Overt hyperglycemia

2.84 (1.19–6.81)

0.019

2.24 (0.83–6.02)

0.112

35.5 (1.93–653.02)

0.002

  1. OR, odds ratio; CI, confidence interval; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; IV tPA, intravenous tissue plasminogen activator; ICA, internal carotid artery; MCA, middle cerebral artery; DWI, diffusion-weighted imaging; mTICI, modified Treatment In Cerebral Ischemia; PH2, parenchymal hematoma type 2; SAH, subarachnoid hemorrhage.
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