Figure 6 | Scientific Reports

Figure 6

From: Myoepithelial cell-driven acini contraction in response to oxytocin receptor stimulation is impaired in lacrimal glands of Sjögren’s syndrome animal models

Figure 6

Decrease in contraction of MECs from NOD mice. Lobules prepared from the lacrimal glands of NOD and BALB/c mice were treated with oxytocin or PBS (vehicle) to stimulate MECs contraction. (A,C) show the basal acinus size in non-stimulated lacrimal glands from BALB/c and NOD mice respectively, while (B,D) show the acinus size after stimulation with 5 nM oxytocin for these mice; respectively. The acinus size was measured using 3 metrics, as depicted in (E). Acinus size was compared using (F) area, (G) perimeter, and (H) Feret’s diameter. Star indicates statistically significant difference compared to the indicated group; n = 3 per group.

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