Figure 6 | Scientific Reports

Figure 6

From: 1-Methyl-D-tryptophan Reduces Tumor CD133+ cells, Wnt/β-catenin and NF-κβp65 while Enhances Lymphocytes NF-κβ2, STAT3, and STAT4 Pathways in Murine Pancreatic Adenocarcinoma

Figure 6

Investigation of NF-κβp65 pathway activity of Pan02 cell line under the effect of 1-MT in vitro illustrated that 1-MT effectively inhibited NF-κβp65 in the tumor cells which proved that 1-Methyl-D-tryptophan efficiently depletes tumorgensis activity and forbid tumor immunosuppressive pathways.

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