Table 2 Selection of immunological pathways that are related to the genes with a different expression in pregnant and non-pregnant females in both BALB/c and B6 mice in the proximal colon (nā=ā5), analyzed with Ingenuity pathways analysis.
Ingenuity Canonical Pathways | p-value B6 | p-value BALB/c | z-score B6 | z-score BALB/c |
|---|---|---|---|---|
Antigen Presentation Pathway | 0.000 | 0.000 | NaN | NaN |
B Cell Development | 0.001 | 0.076 | NaN | NaN |
CD28 Signaling in T Helper Cells | 0.003 | 0.259 | NaN | NaN |
Communication between Innate and Adaptive Immune Cells | 0.039 | 0.000 | NaN | NaN |
Complement System | 0.001 | 0.022 | NaN | NaN |
Crosstalk between Dendritic Cells and Natural Killer Cells | 0.010 | 0.000 | NaN | NaN |
Dendritic Cell Maturation | 0.000 | 0.036 | NaN | NaN |
Differential Regulation of Cytokine Production in Intestinal Epithelial Cells by IL-17A and IL-17F | 0.011 | 0.143 | NaN | NaN |
Granulocyte Adhesion and Diapedesis | 0.000 | 0.006 | NaN | NaN |
iCOS-iCOSL Signaling in T Helper Cells | 0.000 | 0.095 | NaN | NaN |
IL-10 Signaling | 0.163 | 0.048 | NaN | NaN |
IL-4 Signaling | 0.001 | 0.379 | NaN | NaN |
IL-8 Signaling | 0.005 | Ā | ā2.530 | Ā |
IL-9 Signaling | 0.005 | 0.634 | NaN | NaN |
Interferon Signaling | 1.000 | 0.000 | Ā | ā2.449 |
Leukocyte Extravasation Signaling | 0.001 | 0.219 | ā2.121 | 1.134 |
phagosome formation | 0.027 | 0.016 | NaN | NaN |
Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses | 0.120 | 0.012 | ā1.000 | ā0.447 |
T Helper Cell Differentiation | 0.001 | 0.017 | NaN | NaN |
