Figure 5 | Scientific Reports

Figure 5

From: TMUB1 Inhibits BRL-3A Hepatocyte Proliferation by Interfering with the Binding of CAML to Cyclophilin B through its TM1 Hydrophobic Domain

Figure 5

(A,B) The testing of calcium concentration in primary cells. In SPH group, the average of calcium concentration at 0, 12, 24, 48 and 72 hours was 2.99 ± 0.79, 7.39 ± 0.34, 8.46 ± 0.24, 5.54 ± 0.34 and 4.60 ± 0.22, respectively (n = 3 in each time points); In PH group, the average of calcium concentration at 0, 12, 24, 48 and 72 hours was 4.68 ± 0.23, 31.83 ± 0.33, 39.07 ± 0.62, 22.80 ± 0.43 and 14.75 ± 0.38, respectively (n = 3 in each time points). Comparing with SPH group, the calcium concentration in primary cells of PH group was significantly higher at 12, 24, 48 and 72 hours after rat hepatectomy (*P < 0.05, **P < 0.01, t-test). In PH group, the calcium concentration rapidly decreased at 48 hours after hepatectomy when the expression of TMUB1 was significantly higer, which was comfirmed by previous steps (Fig. 1A).

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