Figure 3

Distance map calculations. (a) Fenestrated capillaries visualized by maximum intensity projection of a MECA-32^VT750 brain signal overlaid onto the CCFv3 template³. (b) Maximum intensity projection of average liraglutide^VT750 signal (n = 5) overlaid onto the CCFv3 template³. (c) Coronal projection of the MECA-32^VT750 signal registered to the atlas space and overlaid onto the CCFv3 template³. (d) Distance map constructed from the MECA-32^VT750 signal. The value at a given voxel was assigned as the shortest Euclidian distance to a voxel classified as MECA-32^VT750 positive. Blue indicate voxels close to fenestrated capillaries, while yellow indicate voxels far from fenestrated capillaries. (e) Average liraglutide^VT750 signal overlaid onto a coronal section of the CCFv3 template³. (f) Center of mass distances computed for the liraglutide^VT750 signals described in Fig. 2. The computation was performed in the brain regions marked for discovery in Fig. 2b.