Table 4 Changes in cytokine levels during open heart surgery.
Propofol group (n = 78) | Sevoflurane group (n = 78) | P | |
|---|---|---|---|
IL-1 (%) | |||
Preop | 1.0 (0.5–1.4) | 1.1 (0.6–1.2) | 0.687 |
Weaning | 1.6 (0.8–1.9) | 1.6 (0.9–2.4) | 0.257 |
3 hours | 0.9 (0.5–1.6) | 0.9 (0.5–1.5) | 0.622 |
24 hours | 0.6 (0.4–1.0) | 0.5 (0.3–1.0) | 0.759 |
48 hours | 0.5 (0.2–0.9) | 0.4 (0.2–0.9) | 0.973 |
IL-6 (%) | |||
Preop | 1.7 (0.7–1.9) | 1.7 (0.9–2.0) | 0.535 |
Weaning | 1.9 (1.3–2.0) | 2.4 (1.5–2.6) | 0.050 |
3 hours | 2.2 (0.9–3.7) | 1.8 (1.2–3.8) | 0.894 |
24 hours | 2.1 (1.0–2.8) | 1.6 (0.5–4.0) | 0.296 |
48 hours | 2.1 (0.9–2.7) | 1.5 (0.5–4.0) | 0.318 |
IL-10 (%) | |||
Preop | 2.1 (0.7–3.4) | 2.3 (1.4–4.4) | 0.425 |
Weaning | 1.3 (0.6–2.7) | 1.3 (0.8–2.4) | 0.880 |
3 hours | 1.0 (0.4–2.7) | 1.2 (0.8–1.7) | 0.287 |
24 hours | 2.7 (1.4–3.8) | 3.3 (1.1–4.0) | 0.511 |
48 hours | 2.6 (1.3–3.6) | 3.2 (0.9–3.9) | 0.539 |
IL-17 (%) | |||
Preop | 1.3 (0.5–2.3) | 1.4 (0.3–2.4) | 0.444 |
Weaning | 3.7 (2.8–5.1) | 3.7 (2.9–4.6) | 0.353 |
3 hours | 2.1 (1.2–3.1) | 2.4 (1.7–3.1) | 0.073 |
24 hours | 1.9 (0.8–2.1) | 1.4 (0.2–2.2) | 0.080 |
48 hours | 1.8 (0.8–2.1) | 1.3 (0.1–2.2) | 0.134 |
IFN-γ (%) | |||
Preop | 4.1 (0.8–7.6) | 6.7 (3.7–8.3) | 0.199 |
Weaning | 12.9 (1.0–20.1) | 12.9 (6.7–14.6) | 0.928 |
3 hours | 12.6 (1.0–19.9) | 13.9 (10.4–15.4) | 0.376 |
24 hours | 21.1 (13.1–27.6) | 17.1 (9.5–23.4) | 0.136 |
48 hours | 22.8 (14.9–29.1) | 18.6 (11.1–25.2) | 0.130 |
TNF-α (%) | |||
Preop | 3.3 (1.7–4.1) | 3.1 (2.4–3.8) | 0.982 |
Weaning | 2.5 (0.3–5.1) | 2.9 (0.5–4.8) | 0.272 |
3 hours | 3.4 (2.4–4.0) | 3.0 (1.2–3.9) | 0.153 |
24 hours | 1.5 (0.9–2.0) | 1.2 (0.6–3.2) | 0.357 |
48 hours | 1.3 (0.8–1.8) | 1.1 (0.5–3.1) | 0.396 |
