Figure 5

il10e46/e46 mutation associates with a higher proportion of myeloid cells at 8 weeks post a low-dose (1–18 CFU) M. marinum infection. (a,b) The relative proportions of live cells, lymphocytes, precursor cells and myeloid cells were determined with flow cytometry from the kidneys of il10e46/e46 mutants (n = 10–15) and WT control fish (n = 10–12) at 4 and 8 wpi based on granularity (SSC) and cell size (FSC). The data were collected from a single experiment and are presented as a scatter dot plot and median. A two-tailed Mann-Whitney test was used for the statistical comparison of differences between il10e46/e46 zebrafish and WT controls.