Table 1 Clinical characteristics of 271 HCC patients according to miR-494-3p expression levels.

Feature	miR-494-3p		χ2	p-value
Feature	Low (n = 135)	High (n = 136)	χ2	p-value
All cases
Age, year			0.089	0.807
≥55	61	59
<55	74	77
Gender			0.395	0.550
Male	120	124
Female	15	12
AFP, μg/L			0.306	0.580
Positive	60	65
Negative	75	71
Cirrhosis			0.089	0.802
Present	84	87
Absent	51	49
Tumor size,cm			4.605	0.032
≥5	70	88
<5	65	48
Tumor number			4.189	0.041
Multiple	35	51
Single	100	85
Capsule			1.354	0.273
Present	78	69
Absent	57	67
Vascular invasion			2.016	0.171
Present	58	47
Absent	77	89
TNM stage			6.777	0.012
III–IV	39	60
I-II	96	76
BCLC stage			1.998	0.179
C-D	54	66
A-B	81	70

^#The median expression level was used as the cut-off. Low miR-494-3p expression in each of the 135 patients was defined as a value below the 50th percentile. High miR-494-3p expression in each of the 136 patients was defined as a value above the 50th percentile.
*For analysis of correlation between the expressions levels of miR-494-3p and clinical features, Pearson chi-square tests were used. Results were considered statistically significant at p < 0.05.

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