Figure 6 | Scientific Reports

Figure 6

From: GABA promotes gastrin-releasing peptide secretion in NE/NE-like cells: Contribution to prostate cancer progression

Figure 6The alt text for this image may have been generated using AI.

GABA levels are positively correlated with GRP levels in patients with NE markers. (a) A positive correlation between GABA and GRP levels was found in PCa patients (r = 0.894; p = 0004; n = 10), and when patients were separated, PCa-NE patients had a strong positive correlation (r = 0.961; p = 0.03; n = 4). (b–d) Relative AR, ENO2 (*p < 0.05), GABBR1 (**p < 0.001) gene expression in BPH vs. PCa and BPH vs. PCa-NE, respectively. AR mRNA levels were not significantly different between groups. (e) PCA3 mRNA levels were significantly higher in PCa patients compared to BPH patients (*p < 0.05).

Back to article page