Figure 4 | Scientific Reports

Figure 4

From: The serrulatane diterpenoid natural products RAD288 and RAD289 stimulate properties of olfactory ensheathing cells useful for neural repair therapies

Figure 4

Effect of RAD288 and RAD289 on morphology of mOECs. (a) Representative images of mOECs after drug exposure. Images were segmented with Harmony software using Find Cytoplasm method. Scale bar = 100 µm. (b) Nucleus area of mOECs after treatment with several concentrations of RAD288. (c) Nucleus area of mOECs after treatment with a range of concentrations of RAD289. (d) Cytoplasm area of mOECs after treatment with several concentrations of RAD288. (e) Cytoplasm area of mOECs after treatment with a range of concentrations of RAD289. Negative control (0.2% DMSO) and positive control (1% G5 Supplement) were used. Triplicate wells were used in three separate experiments. Results represent the mean +/− SEM. ***p < 0.001, **p < 0.01, *p < 0.05, Student’s t-test.

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