Figure 3

Rank-ordered distribution of peak intensities in mouse brain, heart, and kidney tissue slices in ROIs of various sizes and comparisons of peak composition between organs. Images of tissue slices of the mouse (A) brain, (B) heart, and (C) kidney analyzed by MALDI IMS (left panels) and their peak intensity rank-ordered distributions (right panels). The colors of distributions is consistent with colors of ROIs shown in the left panel. The dashed line is a reference to the power law distribution. (D) A scatter plot of each peak intensity observed in an averaged spectrum of each whole tissue section (ROI 1 of Fig. 3A–C) and a histogram of the peak numbers binned by the order of intensity observed on only one side tissue. The dashed line refers to unchanged peaks.