Table 3 Comparisons of biochemistry profile between ADHD patients and healthy control children.

From: Attention deficit–hyperactivity disorder is associated with allergic symptoms and low levels of hemoglobin and serotonin

Biochemical indexes

Control (N = 216)

ADHD (N = 216)

Statistic b

p-value

Mean (SD)

Mean (SD)

RBC (1012/L)

4.70 (0.27)

4.64 (0.32)

2.259

0.024

Hb (g/dL)

13.30 (0.85)

13.00 (0.80)

3.466

0.001*

MCV (fL)

84.10 (3.6)

83.00 (4.7)

2.730

0.007

MCH (pg/cell)

28.20 (1.5)

28.10 (1.9)

0.392

0.70

MCHC (g/dL)

33.60 (1.4)

33.90 (1.4)

1.619

0.11

WBC (109/L)

7.02 (1.71)

7.38 (2.11)

1.919

0.06

Neutrophil (%)

49.20 (10.5)

49.80 (9.8)

0.682

0.50

Lymphocyte (%)

39.10 (9.5)

38.30 (8.9)

0.902

0.37

Monocyte (%)

6.83 (1.9)

6.77 (1.83)

0.346

0.73

Eosinophil (%)a

3.78 (2.67)

4.93 (3.62)

3.364

0.001*

Basophil (%)

0.61 (0.85)

0.57 (0.40)

0.553

0.58

Platelet (109/L)

310.00 (66)

314.00 (66)

0.585

0.56

Histamine (nmol/L)a

9.54 (9.18)

9.99 (9.27)

0.461

0.65

CRP (mg/L)a

0.96 (1.66)

1.35 (2.71)

1.470

0.14

IgE (KU/L)a

262.38 (420.27)

367.44 (483.36)

3.559

<0.001*

Serotonin (ng/mL)a

191.61 (88.26)

164.25 (88.39)

4.025

<0.001*

  1. aLog transformation has been done for statistical testing; bChi-square test for groups comparisons of binary variables or t-test for continuous variables, *Statistical significant after Bonferroni correction (p < 0.003125).
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