Figure 6 | Scientific Reports

Figure 6

From: Decoding microglia responses to psychosocial stress reveals blood-brain barrier breakdown that may drive stress susceptibility

Figure 6

Expression levels of select transcripts identifying either hub genes or characterizing biological pathways divergent between microglia from stress stratified mice. (a) Mean expression intensity profile of hub genes in cluster 1 from the microarray. (b) microarray intensity profiles for elevated cluster 1 (green bars) genes grouped by GO analysis. (c) qPCR-derived mRNA expression levels of select cluster 1 genes involved with extracellular matrix (ECM) remodeling (n = 4/group). (d) microarray intensity profiles for elevated cluster 2 hub genes (magenta bar). (e) microarray intensity profiles for selected elevated cluster 4 genes (gray bar). Data show mean ± SD, n = 6 for HC and CSD-S, n = 9 for CSD-R. One-way ANOVA with Bonferroni correction (*p < 0.05, **p < 0.01, ***p < 0.001).

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