Figure 5

RGN-259 increased conjunctival goblet cell densities comparable to that of CsA. (A) Periodic acid Schiff staining. The strong violet color indicates the conjunctival goblet cells. Scale bar = 100 μm. (B) The number of conjunctival goblet cells. *P < 0.05 vs. the corresponding value in the baseline desiccation stressed group. #P < 0.05 vs. the value in the vehicle-treated group. §P < 0.05 vs. the value in the RGN-259, 2 times per day group. †P < 0.05 vs. the value in the RGN-259, 4 times per day group. ¶P < 0.05 vs. the value in the CsA group. ‡P < 0.05 vs. the value in the DQS group. &P < 0.05 vs. the value in the LFA group.