Figure 7

RGN-259 reduced the expression of inflammatory factors comparable to that of CsA and LFA. (A) Immunohistochemistry for inflammatory factors in the lacrimal glands of mice. Scale bar = 100 μm. (B) The quantitative expression of inflammatory factors. *P < 0.05 vs. the corresponding value in the baseline desiccation stressed group. #P < 0.05 vs. the value in the vehicle-treated group. §P < 0.05 vs. the value in the RGN-259, 2 times per day group. †P < 0.05 vs. the value in the RGN-259, 4 times per day group. ¶P < 0.05 vs. the value in the CsA group. ‡P < 0.05 vs. the value in the DQSl group. &P < 0.05 vs. the value in the LFA group.