Figure 1

Typical, normalized ATHP3 and corrected variant (*) mobility profiles for the [M + H]+, [M + 2 H]2+ and [M + 3 H]3+ for intrinsic size parameters upon residue substitution to alanine (a). Peptide IMS fingerprint (b) and correlation matrix (c) are used for assessment of the amino acid sequence effect on the secondary structure.