Table 4 Cytotoxicity of compounds 1–9.
Compounds | Cell lines IC50 (μM) | ||||
|---|---|---|---|---|---|
MDA-MB-231 | MCF-7 | MGC-803 | HeLa | A-549 | |
1 | >10.0 | >10.0 | >10.0 | >10.0 | 1.8 |
3 | 3.3 | 2.8 | 3.6 | 2.9 | 3.2 |
6 | 9.8 | 2.7 | 3.6 | 1.7 | 1.1 |
2, 4, 5, 7, 8, 9 | >10.0 | >10.0 | >10.0 | >10.0 | >10.0 |
Cisplatin | 1.3 | 0.97 | 1.1 | 0.82 | 0.74 |