Table 1 Association of rs6570507 with adolescent idiopathic scoliosis.
Population | Study | Sample number | RAF | P value* | OR (95% CI) | Phet | ||
|---|---|---|---|---|---|---|---|---|
Case | Control | Case | Control | |||||
Japanese | Japan 1 | 1033 | 1473 | 0.49 | 0.42 | 1.37 × 10−6 | 1.32 (1.18–1.48) | |
Japan 2 | 786 | 24466 | 0.48 | 0.43 | 3.02 × 10−5 | 1.24 (1.12–1.37) | ||
Japanese Combined | 1819 | 25939 | 2.15 × 10−10 | 1.28 (1.18–1.38) | 0.40 | |||
Chinese | Nanjing | 743 | 1209 | 0.39 | 0.35 | 3.36 × 10−3 | 1.22 (1.06–1.39) | |
Guangzhou | 647 | 1048 | 0.41 | 0.37 | 2.19 × 10−2 | 1.18 (1.02–1.36) | ||
Hong Kong | 300 | 788 | 0.40 | 0.38 | 4.79 × 10−1 | 1.07 (0.88–1.30) | ||
Beijing | 482 | 861 | 0.37 | 0.34 | 8.93 × 10−2 | 1.15 (0.98–1.36) | ||
Chinese Combined | 2172 | 3906 | 7.79 × 10−5 | 1.17 (1.08–1.26) | 0.75 | |||
East Asian combined | 3991 | 29845 | 2.85 × 10−13 | 1.22 (1.16–1.29) | 0.47 | |||
Caucasian | USA | 1360 | 7267 | 0.34 | 0.30 | 7.95 × 10−6 | 1.22 (1.12–1.33) | |
Scandinavia | 1522 | 1804 | 0.32 | 0.28 | 6.63 × 10−4 | 1.20 (1.08–1.34) | ||
Caucasian Combined | 2882 | 9071 | 1.76 × 10−8 | 1.21 (1.13–1.30) | 0.85 | |||
All combined | 6873 | 38916 | 2.95 × 10−20 | 1.22 (1.17–1.27) | 0.71 | |||
